NIH-National Institute of General Medical Sciences


Kumar, S.; Thornton, P.D.; Santini, C. Diversity by Divergence: Solution Phase Parallel Synthesis of a Library of N-Diversified 1-Oxa-7-Azaspiro[4.5]decan-2-yl-Propanes and -Butanes. ACS Comb. Sci. 2013, 15(11), 564-571. Online access to the article.

Kumar, S.; Thornton, P.D.; Painter, T.O.; Jain, P.; Downard, J.; Douglas, J.T.; Santini, C. Synthesis of a Family of Spirocyclic Scaffolds; Building Blocks for the Exploration of Chemical Space. J. Org. Chem. 2013, 78(13), 6529-6539. Online access to the article.

Painter, T.O.; Bunn, J.R.; Schoenen, F.J.; Douglas, J.T.; Day, V.W.; Santini, C. Skeletal Diversification via Heteroatom Linkage Control: Preparation of Bicyclic and Spirocyclic Scaffolds from N-Substituted Homopropargyl Alcohols. J. Org. Chem.2013, 78(8), 3720-3730. Online access to the article.

Dubrovskiy, A.V.; Jain, P.; Shi, F.; Lushington, G.H.; Santini, C.; Porubsky, P.; Larock, R.C. Solution-Phase Synthesis of a Diverse Library of Benzisoxazoles Utilizing the [3 + 2] Cycloaddition of in Situ-Generated Nitrile Oxides and Arynes. ACS Comb. Sci. 2013, 15(4), 193-201. Online access to the article.

Chandrasomaa, N.; Brown, N.; Brassfield, A.; Nerurkara, A.; Suareza, S.; Buszek, K. R. Total synthesis of (±)-cis-trikentrin B via intermolecular 6,7-indole aryne cycloaddition and Stille cross-coupling. Tetrahedron Letters, 2013, 54(8), 913-917. Online access to the article.

Blake, L. C.; Roy, A.; Neul, D.; Schoenen, F. J.; Aubé, J.; Scott, E. E. Benzylmorpholine Analogs as Selective Inhibitors of Lung Cytochrome P450 2A13 for the Chemoprevention of Lung Cancer in Tobacco Users. Pharmaceutical Research, 2013, 30(9), 2290-2302. Online access to the article.

McCormick, L. F.; Malinakova, H. C. Modular Strategy for the Synthesis of Functionalized Aryl-Fused Azabicyclo[2.2.2]octanes via Sequential Cu/Pd/Ru Catalysis. Journal of Organic Chemistry, 2013, 78(17), 8809-8815. Online access to the article.

Raikar, S. N.; Malinakova, H. C. Divergent Reaction Pathways of Homologous and Isosteric Propargyl Amides in Sequential Ru/Pd-Catalyzed Annulations for the Synthesis of Heterocycles. Journal of Organic Chemistry, 2013, 78(8), 3832-2846. Online access to the article.

Mehta, S.; Waldo, J. P.; Neuenswander, B.; Lushington, G. H.; Larock, R. C. Solution Phase Parallel Synthesis of a Multi-substituted Cyclic Imidate Library. ACS Comb. Sci., 2013, 15, 247-254. Online access to the article.

Markina, N. A.; Chen, Y.; Larock, R. C. Efficient Microwave-assisted One-pot Three-component Synthesis of 2,3-Disubstituted Benzofurans under Sonogashira Conditions. Tetrahedron, 2013, 69, 2701-2713. Online access to the article.

Dubrovskiy, A. V.; Larock, R. C. Intermolecular C-O Addition of Carboxylic Acids to Arynes: Synthesis of o-Hydroxyaryl Ketones, Xanthones, 4-Chromanones, and Flavones. Tetrahedron, 2013, 69, 2789-2798. Online access to the article.

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